In jaundice, which area shows color first?

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Multiple Choice

In jaundice, which area shows color first?

Explanation:
When jaundice develops, bilirubin rise makes tissues take on a yellow tint, and the sclera is where this color appears first. The sclera and the overlying conjunctiva are thin and relatively unpigmented, so even small amounts of bilirubin are visually detectable against the white of the eye. Skin and mucous membranes may stay pale for longer or be masked by melanin, and areas like the palms and soles aren’t as reliable for early detection. So the earliest visible sign is the yellowing of the sclera, often called scleral icterus.

When jaundice develops, bilirubin rise makes tissues take on a yellow tint, and the sclera is where this color appears first. The sclera and the overlying conjunctiva are thin and relatively unpigmented, so even small amounts of bilirubin are visually detectable against the white of the eye. Skin and mucous membranes may stay pale for longer or be masked by melanin, and areas like the palms and soles aren’t as reliable for early detection. So the earliest visible sign is the yellowing of the sclera, often called scleral icterus.

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