Hepatitis B is most commonly transmitted through which route?

• A. Airborne
• B. Fecal-oral
• C. Blood-borne
• D. Contaminated water

Answer: (C)

Hepatitis B is transmitted mainly through contact with infected blood and other body fluids, making blood-to-blood contact, needle sharing, transfusions before screening, and mother-to-child transmission at birth the typical routes. Among the given options, blood-borne spread best fits how HBV spreads. The other routes describe different pathogens: airborne transmission involves small droplets in the air (like TB), fecal-oral spread involves ingestion of contaminated material (typical of Hepatitis A/E and many enteric infections), and contaminated water transmits pathogens like cholera or typhoid. Understanding this helps emphasize why precautions to prevent blood exposure and vaccination are crucial for HBV.