Calcium channel blockers have what effect on AV node conduction?

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Multiple Choice

Calcium channel blockers have what effect on AV node conduction?

Explanation:
Calcium channels drive the slow depolarization that governs AV node conduction. Blocking these L-type calcium channels reduces calcium influx into AV nodal cells, which slows the upstroke of the action potential there. The result is slower passage of impulses from the atria to the ventricles, typically seen as a longer PR interval on ECG. Calcium channel blockers don’t speed conduction, and while they can dampen automaticity in nodal tissue, their main effect in the AV node is to decrease conduction velocity.

Calcium channels drive the slow depolarization that governs AV node conduction. Blocking these L-type calcium channels reduces calcium influx into AV nodal cells, which slows the upstroke of the action potential there. The result is slower passage of impulses from the atria to the ventricles, typically seen as a longer PR interval on ECG. Calcium channel blockers don’t speed conduction, and while they can dampen automaticity in nodal tissue, their main effect in the AV node is to decrease conduction velocity.

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