Adrenergic neurotransmitters include which pair?

• A. Epinephrine and Norepinephrine
• B. Acetylcholine and GABA
• C. Dopamine and Serotonin
• D. Histamine and Glutamate

Answer: (A)

Adrenergic transmission relies on two main catecholamines that bind to adrenergic receptors: epinephrine (adrenaline) and norepinephrine (noradrenaline). These chemicals are produced from tyrosine and are key players in the sympathetic nervous system, with norepinephrine acting mainly as a neurotransmitter and epinephrine being released by the adrenal medulla as a hormone that also acts at receptors. This pairing fits the term adrenergic because they specifically activate adrenergic receptors (alpha and beta types) to produce the fight-or-flight effects.

The other options involve neurotransmitters from different systems: acetylcholine is central to parasympathetic signaling and neuromuscular transmission; GABA is the primary inhibitory transmitter in the CNS; dopamine and serotonin are monoamines with distinct roles in mood and reward; histamine and glutamate serve separate signaling roles in the brain and body.